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abstract

115 - NOCTURNAL ENURESIS - PREVALENCE AND ASSOCIATED LUTS IN ADULT WOMEN ATTENDING A UROGYNAECOLOGY CLINIC.

115

NOCTURNAL ENURESIS - PREVALENCE ANDASSOCIATED LUTS IN ADULT WOMEN ATTENDING A UROGYNAECOLOGY CLINIC.

P. C. CAMPBELL1, W.LI 2, J. E. MONEY-TAYLOR 2, J. DAVIES 1,T. G. GRAY 1, S. C. RADLEY 1;
1SheffieldTeaching Hosp., Sheffield, United Kingdom, 2University ofSheffield, Sheffield Teaching Hosp., Sheffield, United Kingdom.

Introduction: Nocturnal Enuresis(NE) is an under-reported symptom with a profound impact on qualityof life [1]. Nocturnal Enuresis (NE) is defined as involuntary lossof urine which occurs during sleep and can be classified as eitherprimary, persistent primary or secondary [2]. Secondary nocturnalenuresis (SNE) arises after a period of night time dryness of atleast 1 year [3]. There is a paucity of data on prevalence andaetiology of adult SNE in comparison with other types of nocturnalenuresis.
Objective: The objective of this study was toinvestigate the prevalence of NE and its association with other lowerurinary tract symptoms (LUTS) in women attending a urogynaecologyclinic.
Methods: A validated pelvic floor questionnaire(ePAQ-PF) was completed by 2,302 women attending a urogynaecologyclinic over a 3-year period. Association between NE and OAB, stressincontinence and nocturia was assessed using logistic regression.Subgroup analysis was performed on women with NE undergoing TVT.Ethical approval was acquired and statistical analysis performedusing SPSS version 22.
Results: The overall prevalence ofNE reported in the cohort was 23% (536 women). The reporting of NEwas significantly associated with OAB (p<0.005), stressincontinence (p<0.005) and nocturia (p<0.005). Of84 women undergoing TVT, 49% reported NE pre-operatively. These womenreported significantly more severe symptoms of SUI and OAB (p<0.05).Sixty percent reported improvement or cure of NE post-operatively andthis was dependent on improvement or cure of SUI (p<0.005). Thepresence of NE was a negative predictor for improvement in symptomsof stress incontinence following TVT (p=0.037).
Conclusions:This study provides insight into NE, a commonly reported symptom inwomen attending urogynaecology clinics. To our knowledge, this is thefirst study to implicate stress incontinence as an importantaetiological factor in women with NE. Further studies are required tobetter understand the aetiology of NE in adult women and relate thisto management and outcome.
References: 1. Scand J UrolNephrol 1997: 31(6); 533-6. 2. IUJ 2010: 21(5); 5-26.3. Neurol &Urodynamics 2017: 36(1); 188-191.